Relevant Publications


Collaborator – Prof. Mark Buller, Saint Louis University

“Design and Synthesis of Nucleoside Analogs as Viral Polymerase Inhibitors” Bluemling, G. R.; Kuiper, D.L.; Neuman, A.; Hager, M.; Yongfeng, L.; Mao, S.; Thephatri, P.; Prussia, A.; Snyder, J. P.; Natchus, M. G.; Painter, G.; Liotta, D. C., Georgia Life Sciences Summit 2011, Atlanta, GA.

“Drugs from Academia “ Borman, S. Chem. & Engineer. News 2007, 85, 42 - 47.

“Drug Discovery Through Industry-Academic Partnerships” Saag, M. S. Nature Chemical Biology 2006, 2, 649 - 653.

“Emtricitabine, a new antiretroviral agent with activity against HIV and hepatitis B virus” Saag, M. S. Clinical Infectious Diseases 2006, 42 (1).

Collaborator – Prof. Richard Plemper, GA State University

“Synthesis and Metabolic Studies of Host-Directed Inhibitors for Antiviral Therapy” Terry W. Moore, Kasinath Sana, Dan Yan, Stefanie A. Krumm, Pahk Thepchatri, James P. Snyder, José Marengo, Richard F. Arrendale, Andrew J. Prussia, Michael G. Natchus, Dennis C. Liotta, Richard K. Plemper, and Aiming Sun ACS Med. Chem. Lett., 2013, Articles ASAP.

“Asymmetric synthesis of host-directed inhibitors of myxoviruses” Moore, Terry W.; Sana, Kasinath; Yan, Dan; Thepchatri, Pahk; Ndungu, John M.; Saindane, Manohar T.; Lockwood, Mark A.; Natchus, Michael G.; Liotta, Dennis C.; Plemper, Richard K.; Snyder, James P.; Sun Aiming Beilstein J. Org. Chem. 2013, 9, 197-203, No. 23.

“Host-Directed Inhibitors of Myxoviruses: Synthesis and in Vitro Biochemical Evaluation” Sun, Aiming; Ndungu, J. Maina; Krumm, Stefanie A.; Yoon, Jeong-Joong; Thepchatri, Pahk; Natchus, Michael; Plemper, Richard K.; Snyder, James P. ACS Medicinal Chemistry Letters 2011, 2, 798-803.

“Potent host-directed small-molecule inhibitors of myxovirus RNA-dependent RNA-polymerases” Krumm, Stefanie A.; Ndungu, J. Maina; Yoon, Jeong-Joong; Dochow, Melanie; Sun, Aiming; Natchus, Michael; Snyder, James P.; Plemper, Richard K. PLoS One 2011, 6(5), e20069.

“High-throughput screening-based identification of paramyxovirus inhibitors” Yoon, Jeong-Joong; Chawla, Dhruv; Paal, Tanja; Ndungu, Maina; Du, Yuhong; Kurtkaya, Serdar; Sun, Aiming; Snyder, James P.; Plemper, Richard K. Journal of Biomolecular Screening 2008, 13(7), 591-608.

Collaborator – Prof. Richard Plemper, GA State University

“Non-nucleoside Inhibitors of the Measles Virus RNA-Dependent RNA Polymerase: Synthesis, Structure-Activity Relationships, and Pharmacokinetics” Ndungu, J. Maina; Krumm, Stefanie A.; Yan, Dan; Arrendale, Richard F.; Reddy, G. Prabhakar; Evers, Taylor; Howard, Randy; Natchus, Michael G.; Saindane, Manohar T.; Liotta, Dennis C.; Plemper, Richard K.; Snyder, James P.; Sun, Aiming J. Med. Chem. 2012, 55, 4220-4230.

“Target analysis of the experimental measles therapeutic AS-136A” Yoon, Jeong-Joong; Krumm, Stefanie A.; Ndungu, J. Maina; Hoffman, Vanessa; Bankamp, Bettina; Rota, Paul A.; Sun, Aiming; Snyder, James P.; Plemper, Richard K. Antimicrobial Agents and Chemotherapy 2009, 53, 3860-3870.

“Potent Non-Nucleoside Inhibitors of the Measles Virus RNA-Dependent RNA Polymerase Complex” Aiming Sun, Jeong-Joong Yoon, Yan Yin, Andrew Prussia, Yutao Yang, Jaeki Min, Richard K. Plemper, James P. Snyder J. Med. Chem. 2008, 51 (13), 3731-3741.

“Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex activity: Synthesis and in vitro evaluation” Sun, Aiming; Chandrakumar, Nizal; Yoon, Jeong-Joong; Plemper, Richard K.; Snyder, James P. Bioorg & Med. Chem. Lett. 2007, 17, 5199-5203.

“Nonnucleoside inhibitor of measles virus RNA-dependent RNA polymerase complex activity” White, Laura K.; Yoon, Jeong-Joong; Lee, Jin K.; Sun, Aiming; Du, Yuhong; Fu, Haian; Synder, James P.; Plemper, Richard K. Antimicrobial Agents and Chemotherapy 2007, 51, 2293-2303.